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Instruction 1. The material is PE complex nylon with water absorbing resin. Non-toxic and tasteless. 2. Open the water inlet and fill the water less the safety line. Then keep it in refrigerator more than 6 hour. It will become ice cube then you can use it. 3. The ice pack can keep the low temperature for about 12-72 hours. Better packing can keep it longer. 4. The ice pack can be reused many times. Normally you can keep it in refrigerator. 5. It can be widely used in seafood, vegetable, biological reagent, plasma, dairy products delivery and low temperature storage. As well physical cooling when sprain or scald. And questions pls email us