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From the Manufacturers Label:. Benfotiamine is a synthetic derivative of thiamin, belonging to the family of compounds known as allithiamines. .** Benfotiamine is a fat-soluble and more bioavailable and physiologically active than thiamin.** Benfotiamine raised the blood level of thiamin pyrophosphate (TTP), the biologically active coenzyme of thiamin, and stimulates transkotelase, a cellular enzyme essential for maintenance of normal glucose. Manufactured by Doctors Best. ** These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.