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CryoDerm's proprietary blend of MSM, Arnica, Boswella, ILEX, Menthol, Eucalyptus and Peppermint Oil targets the Pain Spasm Cycle, addressing the secondary effects of a subluxation, pain, ischemia, hypertonicity and inflammation. Use CryoDerm Spray, Gel or Roll-On to relieve muscle spasm, reduce inflammation and decrease spindle cell response. CryoDerm Liquid Gel can also be used for massage therapy in place of cream or oil. Its clear water-based formula never balls up or peels off skin and maintains glide. CryoDerm does not contain artificial colors or isopropyl alcohol.