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Product Description The most trusted textbook in medicine -- featuring the acclaimed Harrison's DVD with 57 additional chapters and exclusive video and tutorialsNow presented in TWO VOLUMESAs reviwed by JAMA:"With the 18th edition, Harrison's Principles of Internal Medicine retains its standing as a definitive clinical reference and remains an outstanding foundation for any physician or physician-in-training. In many regards,Harrisons remains synonymous not just with internal medicine but with medicine in general. The editors of the 18th edition have skillfully balanced tradition with the desire and need for innovation. The result is a book that remains as fundamental to current medical practice as the first edition was in 1949."--JAMAExtensively revised and expanded by the worlds leading physicians, Harrisons Principles of Internal Medicine, 18e continues to set the standard as the pinnacle of current medical knowledge and practice, offering the definitive review of disease mechanisms and management.CURRENTAll chapters have been completely updated to reflect the latest knowledge and evidence, and important new chapters have been added, including: "Systems Biology in Health andDisease," "The Human Microbiome," "The Biology of Aging," and "Neuropsychiatric Illnesses in War Veterans."CONNECTEDHarrison's covers more global aspects of medicine than any other textbook, and features such chapters as "Global Issues in Medicine," by Jim Yong Kim, Paul Farmer, and Joseph Rhatigan, and new to the 18th edition, "Primary Care in Low and Middle Income Countries."COMPREHENSIVENo other resource delivers coverage of disease mechanisms and management like Harrison's, including world-renowned chapters on HIV/AIDS, STEMI and non-STEMI myocardial infarction, cancer biology, multiple sclerosis, and diabetes.The Harrisons Multi-Media DVD Better Than Ever!The Harrisons DVD has been expanded to include an extensive video demonstration ofthe neurological physical examination, and video tutorials on how to perform essential clinical procedures, including:ThoracentesisAbdominal ParacentesisEndotracheal IntubationCentral Venous Catheter Placement57 additional chapters and more than 2,000 images make the companion DVD an essential part of every physician's education, practice, and lifelong learning.The DVD also features PowerPoint presentations from fifty chapters to facilitate classroom lectures, and a free trial subscription to AccessMedicine.com (including Harrison's Online).Harrisons 18e is proud to present a tribute to longtime editor, Eugene Braunwald, MDfor his outstanding and continuing contributions to medical knowledge and practice. About the Author About the EditorsDan L. Longo, MD,Lecturer, Department of Medicine, Harvard Medical SchoolSenior Physician, Brigham and Women's HospitalDeputy Editor, New England Journal of MedicineBoston, MAAdjunct Investigator, National Institute of AgingNational Institutes of HealthBethesda, MDDennis L. Kasper, MDWilliam Ellery Channing Professor of MedicineProfessor of Microbiology and Molecular GeneticsHarvard Medical SchoolDirector, Channing Laboratory, Department of MedicineBrigham and Women's HospitalBoston, MAJ. Larry Jameson, MD, PhDRobert G. Dunlap Professor of MedicineDean, University of Pennsylvania School of MedicineExecutive Vice-President of the University ofPennsylvania for the Health SystemPhiladelphia, PAAnthony S. Fauci, MDChief, Laboratory of ImmunoregulationDirector, National Institute of Allergy and InfectiousDiseases, National Institute of HealthBethesda, MDStephen L. Hauser, MDRobert A. Fishman Distinguished Professor and ChairmanDepartment of NeurologyUniversity of California, San FranciscoSan Francisco, CAJoseph Loscalzo, MD, PhDHersey Professor of the Theory and Practice of MedicineHarvard Medical SchoolChairman,Department of MedicinePhysician-in-Chief, Brigham and Women's HospitalBoston, MA