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What Are Rutin Supplements? Rutin supplements contain a powerful antioxidant (rutin) known as a flavonol found in many plants and citrus fruits. Rutin Supplements Benefits Rutin supplements have a wide range of benefiting properties. They support the joints, bones, skin, liver, eyes, and lungs.* Rutin fortifies immune function, aids digestion, and works to aid metabolic function.* In addition, rutin supplements work to support the cardiovascular and heart function.* Rutin also works to support the brain, aid memory and cognition, and support nerve function.