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About Tissue Engineering
Product Description This bookthe first in its fieldlays the foundation for individuals studying tissue engineering. It provides a conceptual framework that includes exposure to all the necessary background material in all areas. A four-part presentation covers quantitative cell and tissue biology, cell and tissue characterization, engineering methods and design, and clinical implementation. For cell culture scientists and engineers. From the Back Cover Tissue engineering is a complex and emerging field of study that combines basis biological sciences (molecular, cell, and tissue biology and physiology), engineering fundamentals (fluid mechanics, transport phenomena, materials science, chemical kinetics), clinical aspects (surgery, transplantation, immunology, pathology, radiology) and biotechnology (cell culture, cell separations, gene transfer). All these disciplines converge to study of tissue dynamics that coordinate tissue repair, replacement, and reconstruction. These are procedures and therapies in which cells themselves act as the therapeutic agents. This book on tissue engineering is the first textbook in this field and it offers the convergence of important fundamental concepts in biology, engineering, medicine, and biotechnology. These diverse concepts are carefully organized and laid out in a clear framework to orient students entering the field. This framework includes four parts: Part I: Quantitative Cell and Tissue Biology?Including tissue organization, tissue dynamics, morphogenesis, stem cells, cellular fate processes, and their coordination.Part II: Cell and Tissue Characterization-Including high-throughput technologies, cell and tissue properties, cell and tissue culture, and gene transferPart III: Engineering Methods and Design-Including time constant analysis, scale-up procedures, cell separations, biomaterial scaffolds, and how to tailor biomaterialsPart IV: Clinical Implementation-Including conventional approaches to tissue repair, host integration, and producing tissue-engineered therapies. This book thus offers the basics of this emerging field to the student and a framework in which instructors can build comprehensive courses, with the flexibility to emphasize and expand on any particular topic. Excerpt. © Reprinted by permission. All rights reserved. Tissue engineering holds the promise to repair or replace damaged organs. As a discipline, the field has evolved dramatically from its origins in the late 1980s. In particular, the rapid advances in stem cell biology have rekindled the enthusiasm use cell-based approaches for the treatment of disease. For success in this area, must learn to manipulate, produce, and deliver collections of cells as building blocks of tissues. Transplanted cells and tissue constructs are influenced by their microenvironment and can be manipulated to effectively interact with patients. The underpinnings of tissue engineering are thus broad, and span a wide spectrum of scientific and engineering fundamentals. This list includes basic biological sciences (cell biology, physiology, embryology, and wound healing); engineering fundamentals (fluid dynamics, transport phenomena, materials science, mechanics, and chemical kinetics); many clinical aspects (surgery and transplantation, immunology, pathology, radiology, and medicine), and various relevant biotechnologies (cell culture, cell separation, and gene transfer). This long list of specialized knowledge makes it challenging to organize all the necessary background material for the student of tissue engineering in a clear and succinct manner. In writing this book, we aimed to lay the foundation for students studying tissue engineering at both the undergraduate and the graduate level. We have attempted to provide a conceptual framework that includes exposure to all of the necessary background material. Thus, we cannot treat any particular subject in great detail but rather can provide the neede
