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Essentials of Pharmaceutical Preformulation
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About Essentials Of Pharmaceutical Preformulation
Essentials of Pharmaceutical Preformulation is a studyguide which describes the basic principles of pharmaceuticalphysicochemical characterisation. Successful preformulationrequires knowledge of fundamental molecular concepts (solubility,ionisation, partitioning, hygroscopicity and stability) andmacroscopic properties (physical form, such as the crystalline andamorphous states, hydrates, solvates and co-crystals and powderproperties), familiarity with the techniques used to measure themand appreciation of their effect on product performance,recognising that often there is a position of compromise to bereached between product stability and bioavailability.This text introduces the basic concepts and discusses theirwider implication for pharmaceutical development, with reference tomany case examples of current drugs and drug products. Specialattention is given to the principles and best-practice of theanalytical techniques that underpin preformulation (UVspectrophotometry, TLC, DSC, XRPD and HPLC). The material ispresented in the typical order that would be followed whendeveloping a medicine and maps onto the indicative pharmacysyllabus of the Royal Pharmaceutical Society of Great BritainUndergraduate-level pharmacy students and R&D / analyticalscientists working in the pharmaceutical sector (with or without apharmaceutical background) will find this text easy to follow withrelevant pharmaceutical examples.Essential study guide for pharmacy and pharmaceutical sciencestudentsCovers the pharmaceutical preformulation components of theRoyal Pharmaceutical Society of Great Britain’s indicativesyllabusEasy to follow text highlighted with relevant pharmaceuticalexamplesSelf-assessment assignments in a variety of formatsWritten by authors with both academic and industrialexperienceCompanion website with further information to maximiselearning
