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Stability testing (according to ICH Q1A) in the pharmaceutical industry, long-term storage, growing plants, conditioning and climate testing of plastic material/metal/composite material, storage of electronic components/lacquers/ coatings in controlled environment. They are simply unbeatable in energy efficiency. Furthermore, as constant climate chambers HPP have a very long, maintenance free service life, they are perfectly suited for stability tests, storage in controlled environment and conditioning. The high precision temperature control from 0 °C to +70 °C as well as active humidification and dehumidification from 10 % to 90 % rh were particularly adapted to the ICH guidelines, option Q1A, for stability tests. In a Memmert climate chamber HPP750life mice can be kept in a "specific pathogen free" (SPF) state. Ideally the climate chamber is located in a clean room. In order to guarantee the recommended humidity of between 45 and 65 % rh for the humane keeping of mice even at low temperatures, Memmert integrated a compressed air drying unit. For simulation of the day and night rhythm, the LED illumination can be programmed using the AtmoCONTROL software.