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Edvotek 118 Cholesterol Diagnostics for 8 Gels
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About Edvotek 118 Cholesterol Diagnostics For 8 Gels
Elevated blood cholesterol has been established as a serious risk factor for coronary heart disease and stroke which are leading causes of death in the United States. A disease known as familial hypercholesterolemia (FH) causes an increase in blood levels of the "bad" form of cholesterol, known as low density lipoprotein (LDL). In this experiment, a simulated genetic test for FH is demonstrated in which patients are tested for a DNA polymorphism linked to the FH gene. Kit includes: instructions, Ready-to-Load DNA samples, UltraSpec-Agarose powder, practice gel loading solution, electrophoresis buffer, InstaStain Blue and FlashBlue stain, calibrated pipet, 100 ml graduated cylinder, and microtipped transfer pipettes. All you need: electrophoresis apparatus, power supply, automatic micropipet and tips, balance, microwave or hot plate, visualization system. DNA samples are stable at room temperature. However, if the experiment will not be conducted within one month of receipt, it is recommended that the DNA samples be stored in the refrigerator. DNA samples do not require heating prior to gel loading. A: DNA Standard Markers, B: Normal DNA Sample, C: FH Control, D: Patient #1 DNA Sample, E: Patient #2 DNA Sample, F: Patient #3 DNA Sample.
