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0219134490-500 g - Cathepsin G. 95%. Powder - Each (500G) - Each
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About 0219134490-500 G - Cathepsin G. 95%. Powder - Each
The amount of enzyme that hydrolyzes one mole of Suc-ala-ala-pro-phe-pNA (1mM) per minute 25 C in pH 7.5, with 1.6 M NaCl. Inhibitors: Chymostatin, DFP Cathepsin G act as a bacteriocidal reagent. Catrhepsin G is often referred to as a chymotrypsin-like enzyme, since it preferentially cleaves proteins on the carboxyl side of leucine, methionine, and phenylalanine. Cathepsin G can be assayed with substrates such as azocasein, Suc-Ala-Ala-Pro-Phe-NPhNO2, and MeOSUC-Ala-Ala-Pro-Met-NPh-NO2. Cathepsin G also has a specificity of action on the oxidized B chain of insulin and on BSA, which indicates a closer similarity to porcine chymotrypsin C than to bovine chymotrypsin A. Cathepsin G has pro-apoptotic activity and can activate caspases in vitro.
