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Opcon-A Antihistamine and Redness Reliever Eye Drops combine an antihistamine for itch relief with a redness reliever. Available without a prescription, Opcon-A eye drops temporarily relieve the itching and redness caused by pollen, ragweed, grass, animal hair, and dander. They can be used up to four times a day. Opcon-A Eye Allergy Relief Itching & Redness Reliever Eye Drops . 5 Fl Oz Clinically proven to provide effective relief of itchy, red eyes. Combination antihistamine and redness reliever formula. For use by adults and children 6 years of age and older.