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Apply liberally in a DIRTY ear to fill the canal. Gently massage and work into infected area. Wipe to remove excess. Treat once a day for 7 days, 14 for chronic. Flush ear post-treatment. Now also available in Clinic Size 8 oz. bottle to provide product availability for initial in-house treatment. Replace initial cleanings with initial treatments to guarantee optimal product results. May be safely used for a longer period on hard to treat, resistant microorganisms. Some ear infections may take up to 1 to 2 months to resolve. Zymox Otic Enzymatic Solution Available with or without Hydrocortisone.