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The Alliance Organ Donation Exploratory Seminar is an interactive course, developed and delivered by field experts, to broadly examine the comprehensive donation process for the multidisciplinary healthcare team. This course introduces the clinical, legal and administrative considerations of organ donation, as well as synergistic healthcare partnerships and patient family dynamics. It has been developed specifically with clinicians and front-line healthcare team members in mind – creating a shared understanding of the complex and interconnected logistics of organ donation and bolstering effective practices in hospitals where donation occurs.This textbook is an anthology of essays written by renowned experts in the field, including intensivists, healthcare professionals, legal practitioners, communications experts and donor families. Each chapter appears in the style and vernacular of its respective author and demonstrates their years of invaluable experience. The goal of this publication is to provide the reader with a comprehensive scope of understanding in the field of donation and transplantation, as well as stimulate insightful conversation and critical thinking. This publication is intended for reference only and is not intended to take the place of professional judgment in one’s own practice setting.